It seems like RNA interference might be an opportunity to modfy ourselves in easy and more predictable way (compared to actually genetically modifying ourselves), and I wonder if we should start a project or two around that? For those of you who don't already know, here's the short version of how it works.
If RNA is introduced to the cell which is complementary to messenger RNA, then the resulting double stranded RNA will be destroyed by the cell, which assumes all dsRNA is viral. The fragments of these sequences then continue to bind to more messenger RNA, silencing the expression of that gene for as long as they are present in the cell.
This complementary RNA should be pretty easy to produce and purify in a bacterial vector, if we run a column using a polyA tag (aka the one normally present in mRNA), since naturally occuring sequences don't usually have a bunch of T at one end.
My first idea for a use is (along with a postgrad friend of mine) to knock out a pigment in the iris in order to change eye colour, though that would depend on the turnover rate of pigment there, but other suggestions are welcome. So, advice? Support? Reasons why it's doomed to fail?