Tideglusib - regrowing tooth enamel
I've got 5mg of Tideglusib. The SDS says to dissolve it in DMSO. I have DMSO arriving soon. I am thinking I'd find a tiny sponge on a stick applicator, and apply the Tideglusib solution to my cavities on a nightly basis. Any suggestions of tine sponge applicators?
This is what the SDS says and I don't quite understand it.
Solubility Notes: ~0.5 mg/ml in 1:1 DMSO:PBS (pH 7.2); ~1 mg/ml in DMSO & DMF;
The animal studies consisted of them drilling a hole to the denten, the putting a sponge with the Tideglusib absorbed in it, and sealing it in the hole. After a few weeks the hole sealed up.
I think I'd best use 10ml of DMSO to dissolve the 5mg in. If I get a small enough sponge applicator, not a q-tip because that would be extremely wasteful, then I would be able to dab a tiny coating nightly.
I'd particularly like that 10ml to last 30 days, so I need the tiniest amount on the applicator.
One concern is the DMSO being so readily absorbable, that I don't want to hurt my tongue, gums, and cheeks.
I apply 2% iodine onto my cavities weekly with a q-tip. I am not too careful and I do taste the iodine and spit it out afterwards. I want to be a bit more careful with the Tideglusib to not waste it or get on my gums and such.