Telomerase Reverse Transcriptase Enzyme Injections for Improving Longetivity
Hello. I was hoping that some people could help me think about this. I was thinking that telomerase reverse transcriptase enzyme could be injected intravenously, and that cell receptors would pick it up, and voila, rejuvenated telomeres. You can purchase this enzyme for about $150, which, seeing that you would only injected every couple of years or so, would be an acceptable price for anyone of any budget who wants to live longer. Do you think that this could work? If not, please feel free to correct me and point out what I have missed. Thank you!
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Many cancer cells, which split by mitosis at a very fast pace, have been shown to have quite short telomeres at the ends of their chromosomes.
Elderly people's chromosomes have shorter telomeres mostly because all enzymes in our bodies, including the telomerase, start working at a slower pace as years pass by. And that's quite physiological, as our whole metabolism begins slowing down with aging.
Moreover, as glims pointed out, injecting intravenously is utterly pointless if there are no receptors ready to catch the enzyme on your cell membranes.
Rather than simply shooting up this enzyme, modifying a virus so that it can attack the cells and extend the telomeres in this way. I think this is what BioViva basically did? I know it may not be proven but say one wants to try this method anyway. Where's a good start for someone interested in modifying a virus in this manner?
Proposed game plan here would basically be to create your viral culture, plummet your own immune system, expose yourself until the virus catches on and multiplies then let it run its course through you. Where though does one start on learning to create such a culture? I know this is one of those "if you have to ask you shouldn't be modifying your own genes" but for academic sake...