The biohack.me forums were originally run on Vanilla and ran from January 2011 to July 2024. They are preserved here as a read-only archive. If you had an account on the forums and are in the archive and wish to have either your posts anonymized or removed entirely, email us and let us know.
While we are no longer running Vanilla, Patreon badges are still being awarded, and shoutout forum posts are being created, because this is done directly in the database via an automated task.
Bioactive Glass Toxicology
I was wondering if anyone has done some research on the toxicology/biocompatibility of implants. Heavy metal exposure from these implants is definitely a concern, and it seems as though bioactive glass has very little information as well.
Does anyone have access to this paper?
Toxicology and biocompatibility of bioglasses (J Wilson et al, 1981)
https://onlinelibrary.wiley.com/doi/pdf/10.1002/jbm.820150605
It also seems like some of these magnets are coated in gold and cobalt. I would definitely advise against using these implants. ( /discussions/2365?page=1#latest )
Comments
-
The paper you linked concluded:
"We feel that any material which allows close contact of living cells at its surface, which does not contain leachables which produce inflammation and which does not prevent growth and division of cells in culture, can be considered biocompatible. Such materials are the bioglasses used in the experiments described here. "I personally think the Bio-Bond coating (polypropylene) is worth more concern, though even that may be unfounded.
Transponder-Induced Sarcoma in the Heterozygous p53+/- Mouse
http://journals.sagepub.com/doi/pdf/10.1177/019262339902700505 -
That's a great paper thanks. I'd never actually considered using implants for animal testing.
Biomedic, the company making the implant in this paper has some other research on their devices.
https://www.bmds.com/uploads/files/Tissue_Reaction_Txp.pdf
Seems like all of these implants regardless of the coating might be causing inflammation and cell proliferation.
-
Also a great paper! I think that's the big problem with any implant- there is no way so far to mitigate the foreign body response
