nicotine as a ngf

i recently watched a video by bulletproof describing some of the ngf's that are out there and one of them was nicotine. in small doses the guy said it wasn't harmful and was in fact helpful. i make my own vape juice and wanted to know if i put nicotine in it would inhaling it give me the effect im looking for and how much would i need to administer to my e liquid for it to give this effect
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