Auditory hair cell regeneration

A study (linked below) published in Neuron in 2012 reported a return of hearing in rats related to transdifferentiation of support cells into hair cell after administration of a y-secretase inhibitor compound. I haven't really looked into this much but it seems very interesting. Below are links including sourcing of some Y-secretase compounds.

 

http://en.wikipedia.org/wiki/Gamma_secretase

http://www.ncbi.nlm.nih.gov/pubmed/23312516

http://www.scbt.com/chemicals-table-gamma-secretase_inhibitors.html

 

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Comments

  • I've just downloaded the article in it's entirety.  I will be looking it over.  This is very interesting, thank you.
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